CNP
C-type natriuretic peptide
Data not indexed yet
0 studies
Open record →Scientific Topic
Chondrocytes
Células especializadas da cartilagem e da placa de crescimento.
At a glance
Research Summary
- What is it?
- Células especializadas da cartilagem e da placa de crescimento.
- Why does it matter?
- This topic provides a conceptual bridge between 2 biological processes and 2 compounds.
- Key mechanisms
- CNP / NPR-B Signaling
- Key targets
- NPR2 / NPR-B
- Related compounds
- CNP · Vosoritide
- Human evidence
- No human studies indexed for this node.
- Main uncertainties
- The current index is curated but not exhaustive.
Biological context
BI
Growth Plate
biological process
Chondrocyte proliferation, hypertrophy, differentiation and endochondral ossification.
15 pathway5 target12 compound7 study→
BIEndochondral Ossification
biological process
Replacement of a cartilage template by bone during development and repair.
12 pathway3 target6 compound1 study→
CEOsteoblasts
cell type
Bone-forming cells that synthesize osteoid and participate in mineralization.
5 pathway3 target6 compound1 study→
CEOsteoclasts
cell type
Multinucleated cells specialized for resorption of mineralized bone.
5 pathway3 target6 compound1 study→
CEOsteocytes
cell type
Mature bone cells embedded in matrix that participate in mechanosensing and remodeling signals.
5 pathway3 target5 compound1 study→
CEChondrocytes
cell type
Primary cell type responsible for cartilage matrix formation and growth-plate activity.
10 pathway3 target4 compound1 study→
Related Compounds
Related Pathways
Evidência publicada
Estudos
No dead ends
Continue Exploring
CO
CNP
compound
C-type natriuretic peptide
12 pathway4 target9 compound1 study→
COVosoritide
compound
CNP analogue
12 pathway4 target8 compound1 study→
PACNP / NPR-B Signaling
pathway
Sinalização do receptor guanilato ciclase NPR-B por CNP, relevante à biologia da cartilagem de crescimento.
9 pathway4 target10 compound1 study→