Semax
ACTH-derived synthetic peptide
Mecanismo estruturado ainda não indexado.
Data not indexed yet
0 studies
Open record →Tissue
Brain
Central nervous system tissue integrating neural, endocrine and metabolic signals.
At a glance
Research Summary
- What is it?
- Central nervous system tissue integrating neural, endocrine and metabolic signals.
- Why does it matter?
- This tissue provides anatomical context for 0 cell types and 5 connected pathways.
- Key mechanisms
- GLP-1 Signaling · Melanocortin Signaling · cAMP Signaling · AMPK · Glucagon Signaling
- Key targets
- GLP1R · MC1R · GIPR · GCGR
- Related compounds
- Semax · Selank · Kisspeptin-10 · Kisspeptin-54 · Gonadorelin · PT-141 / Bremelanotide
- Human evidence
- No human studies indexed for this node.
- Main uncertainties
- The current index is curated but not exhaustive.
Biological processes
Relevant pathways
PA
GLP-1 Signaling
pathway
Sinalização de GLP-1R relacionada a secreção de insulina, esvaziamento gástrico e circuitos de saciedade.
6 pathway4 target19 compound7 study→
PAMelanocortin Signaling
pathway
Família de receptores ativados por peptídeos derivados de POMC, com funções dependentes do subtipo receptor e tecido.
3 target26 compound→
PAcAMP Signaling
pathway
Rede de segundo mensageiro gerada por adenilil ciclase e interpretada por efetores como PKA e EPAC.
6 pathway5 target20 compound7 study→
PAAMPK
pathway
Sensor celular de energia que coordena respostas ao estado energético.
5 pathway4 target11 compound2 study→
PAGlucagon Signaling
pathway
Sinalização de GCGR com efeitos metabólicos predominantes no fígado e dependentes do estado nutricional.
2 pathway3 target8 compound→
Related Compounds
Selank
Tuftsin-derived synthetic peptide
Mecanismo estruturado ainda não indexado.
Data not indexed yet
0 studies
Open record →Kisspeptin-10
Kisspeptin fragment
Mecanismo estruturado ainda não indexado.
Data not indexed yet
0 studies
Open record →Kisspeptin-54
Endogenous kisspeptin isoform
Mecanismo estruturado ainda não indexado.
Data not indexed yet
0 studies
Open record →Gonadorelin
Synthetic GnRH
Mecanismo estruturado ainda não indexado.
Data not indexed yet
0 studies
Open record →PT-141 / Bremelanotide
Melanocortin receptor agonist
Data not indexed yet
0 studies
Open record →Retatrutide
GIPR / GLP-1R / GCGR agonist
Data not indexed yet
0 studies
Open record →Tirzepatide
GIPR / GLP-1R agonist
Data not indexed yet
0 studies
Open record →Semaglutide
GLP-1 receptor agonist
Human RCT
1 study
Open record →Evidência publicada
Estudos
No dead ends
Continue Exploring
TA
GLP1R
target
GLP1R is a class b g protein-coupled receptor connected to Gs, Adenylyl cyclase, cAMP, PKA / EPAC.
6 pathway3 target14 compound1 study→
BINeuroplasticity
biological process
Activity-dependent changes in neural structure, connectivity and function.
2 pathway4 target9 compound1 study→
COSemax
compound
ACTH-derived synthetic peptide
2 pathway4 target8 compound1 study→
COSelank
compound
Tuftsin-derived synthetic peptide
2 pathway4 target8 compound1 study→
COKisspeptin-10
compound
Kisspeptin fragment
9 pathway7 target18 compound7 study→
COKisspeptin-54
compound
Endogenous kisspeptin isoform
9 pathway7 target18 compound7 study→
COGonadorelin
compound
Synthetic GnRH
9 pathway7 target18 compound7 study→
COPT-141 / Bremelanotide
compound
Melanocortin receptor agonist
9 pathway7 target20 compound7 study→