Retatrutide
GIPR / GLP-1R / GCGR agonist
Data not indexed yet
0 studies
Open record →Biological Target
GIPR
Glucose-dependent insulinotropic polypeptide receptor
GIPR is a class b g protein-coupled receptor connected to Gs, cAMP.
At a glance
Research Summary
- What is it?
- Receptor: Class B G protein-coupled receptor
- Why does it matter?
- This target connects ligands and 2 indexed compounds to downstream signaling.
- Key mechanisms
- Not indexed yet
- Key targets
- GIPR
- Related compounds
- Retatrutide · Tirzepatide
- Human evidence
- 0 related study records are currently indexed.
- Main uncertainties
- Tissue expression and downstream effects vary by cell state, dose and experimental context.
Target profile
Canonical details
- Canonical name
- GIPR
- Aliases
- Glucose-dependent insulinotropic polypeptide receptor
- Target type
- Receptor
- Receptor class
- Class B G protein-coupled receptor
- Endogenous ligands
- GIP
- Downstream signaling
- Gs → cAMP
Curated relationships
direct
Retatrutide acts on GIPR.
scope not indexeddirect
Tirzepatide acts on GIPR.
scope not indexedPathways, tissues and cells
TI
Brain
tissue
Central nervous system tissue integrating neural, endocrine and metabolic signals.
5 pathway5 target24 compound1 study→
TIGI Tract
tissue
Digestive tissues that also produce and respond to peptide signals.
4 pathway3 target13 compound1 study→
TIAdipose Tissue
tissue
Energy-storing and endocrine tissue composed of adipocytes and stromal cells.
7 pathway5 target25 compound2 study→
Related Compounds
Tirzepatide
GIPR / GLP-1R agonist
Data not indexed yet
0 studies
Open record →Evidência publicada
Estudos
Nenhum estudo desta categoria de evidência foi indexado para este nó.
No dead ends