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AnimalRat / wound tissue

Expression and activation of matrix metalloproteinases in wounds: modulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+

A. Siméon, F. Monier, H. Emonard, P. Gillery, P. Birembaut, W. Hornebeck, F. X. Maquart

Journal of Investigative Dermatology1999DOI 10.1046/j.1523-1747.1999.00606.xPubMed 10383745

Study design

Methods snapshot

Population
Experimental wounds
Sample size
Not indexed
Intervention
GHK-Cu
Route
Not indexed
Dose reported
Not indexed
Frequency
Not indexed
Duration
Not indexed
Control / placebo
Not indexed

Outcomes

Primary

  • Matrix metalloproteinase expression and activation

Results

The study reported modulation of wound-associated matrix metalloproteinases following GHK-Cu exposure.

Interpretation

Supports context-dependent matrix-remodeling activity.

Adverse events

Not indexed in the current record.

Limitations

  • Experimental wound model

Connected records

Original source

Sempre consulte o artigo original para métodos completos, análises e contexto editorial.

Open PubMed record ↗