Human RCTHumanRandomizedBlindedControlled
Enhanced healing of ulcers in patients with diabetes by topical treatment with glycyl-l-histidyl-l-lysine copper
G. D. Mulder, L. M. Patt, L. Sanders, J. Rosenstock, M. I. Altman, M. E. Hanley, G. W. Duncan
Study design
Methods snapshot
- Population
- Patients with diabetic neuropathic plantar ulcers receiving standardized wound care
- Sample size
- Not indexed
- Intervention
- GHK-Cu
- Route
- Topical
- Dose reported
- Metered dose of Lamin gel; amount not reported in the indexed abstract
- Frequency
- Daily
- Duration
- Not indexed
- Control / placebo
- Controlled study
Outcomes
Primary
- Ulcer area closure
- Rate of closure
- Ulcer infection
Results
The report described greater median plantar-ulcer closure and faster closure with topical GHK-Cu gel than vehicle under standardized wound care.
Interpretation
Limited human evidence for one topical wound-care formulation and population.
Adverse events
- The abstract reported a lower incidence of ulcer infection in the immediate-treatment group.
Limitations
- Older indication-specific trial
- Full protocol and sample size require full-text verification
- Cannot be generalized to intact-skin aesthetic use
Connected records
Compounds
GHK-CuTopics
Wound HealingOriginal source
Sempre consulte o artigo original para métodos completos, análises e contexto editorial.
Open PubMed record ↗