In VitroModel membrane
ESI-MS study of the mechanism of glycyl-l-histidyl-l-lysine-Cu(II) complex transport through model membrane of stratum corneum
L. Mazurowska, M. Mojski
Study design
Methods snapshot
- Population
- Flynn diffusion-cell liposome membrane model
- Sample size
- Not indexed
- Intervention
- GHK-Cu
- Route
- Not indexed
- Dose reported
- Not indexed
- Frequency
- Not indexed
- Duration
- Not indexed
- Control / placebo
- Not indexed
Outcomes
Primary
- Complex formation and membrane permeability
Results
GHK and its copper complexes crossed the model membrane, with permeability dependent on experimental pH and complex form.
Interpretation
Mechanistic permeation evidence only.
Adverse events
Not indexed in the current record.
Limitations
- Model membrane is not intact human skin
- No clinical outcome
Connected records
Original source
Sempre consulte o artigo original para métodos completos, análises e contexto editorial.
Open PubMed record ↗