Afamelanotide
α-MSH analogue
Data not indexed yet
0 studies
Open record →Scientific Topic
Melanogenesis
Produção e distribuição de melanina por melanócitos.
At a glance
Research Summary
- What is it?
- Produção e distribuição de melanina por melanócitos.
- Why does it matter?
- This topic provides a conceptual bridge between 1 biological processes and 2 compounds.
- Key mechanisms
- Melanocortin Signaling
- Key targets
- MC1R
- Related compounds
- Afamelanotide · Melanotan II
- Human evidence
- No human studies indexed for this node.
- Main uncertainties
- The current index is curated but not exhaustive.
Biological context
BI
Pigmentation
biological process
Melanin synthesis and distribution through melanocortin-dependent and local signaling.
4 pathway1 target4 compound15 study→
CEFibroblasts
cell type
Mesenchymal cells that synthesize and remodel extracellular matrix in connective tissues.
4 pathway1 target7 compound15 study→
CEKeratinocytes
cell type
Predominant epidermal cells that form and renew the skin barrier.
4 pathway1 target7 compound15 study→
CEMelanocytes
cell type
Pigment-producing cells that synthesize melanin and transfer melanosomes to keratinocytes.
4 pathway1 target8 compound15 study→
Related Compounds
Melanotan II
Cyclic melanocortin analogue
Data not indexed yet
0 studies
Open record →Related Pathways
Published evidence
Studies
No studies in this evidence category are indexed for this node.
No dead ends
Continue Exploring
CO
Afamelanotide
compound
α-MSH analogue
4 pathway1 target7 compound15 study→
COMelanotan II
compound
Cyclic melanocortin analogue
4 pathway1 target7 compound15 study→
PAMelanocortin Signaling
pathway
Família de receptores ativados por peptídeos derivados de POMC, com funções dependentes do subtipo receptor e tecido.
3 target26 compound→