Retatrutide
GIPR / GLP-1R / GCGR agonist
Data not indexed yet
0 studies
Open record →Tissue
GI Tract
Digestive tissues that also produce and respond to peptide signals.
At a glance
Research Summary
- What is it?
- Digestive tissues that also produce and respond to peptide signals.
- Why does it matter?
- This tissue provides anatomical context for 0 cell types and 4 connected pathways.
- Key mechanisms
- GLP-1 Signaling · AMPK · cAMP Signaling · Glucagon Signaling
- Key targets
- GIPR · GLP1R · GCGR
- Related compounds
- Retatrutide · Tirzepatide · Semaglutide
- Human evidence
- No human studies indexed for this node.
- Main uncertainties
- The current index is curated but not exhaustive.
Relevant pathways
PA
GLP-1 Signaling
pathway
Sinalização de GLP-1R relacionada a secreção de insulina, esvaziamento gástrico e circuitos de saciedade.
6 pathway4 target19 compound7 study→
PAAMPK
pathway
Sensor celular de energia que coordena respostas ao estado energético.
5 pathway4 target11 compound2 study→
PAcAMP Signaling
pathway
Rede de segundo mensageiro gerada por adenilil ciclase e interpretada por efetores como PKA e EPAC.
6 pathway5 target20 compound7 study→
PAGlucagon Signaling
pathway
Sinalização de GCGR com efeitos metabólicos predominantes no fígado e dependentes do estado nutricional.
2 pathway3 target8 compound→
Related Compounds
Tirzepatide
GIPR / GLP-1R agonist
Data not indexed yet
0 studies
Open record →Semaglutide
GLP-1 receptor agonist
Human RCT
1 study
Open record →Published evidence
Studies
No dead ends