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Biological Target

GHSR

GHS-R1a · Ghrelin receptor

GHSR is a class a g protein-coupled receptor connected to Gq/11, PLC, Intracellular calcium.

At a glance

Research Summary

What is it?
Receptor: Class A G protein-coupled receptor
Why does it matter?
This target connects ligands and 4 indexed compounds to downstream signaling.
Key mechanisms
Ghrelin / GHSR
Key targets
GHSR
Related compounds
Ipamorelin · GHRP-2 · GHRP-6 · Hexarelin
Human evidence
0 related study records are currently indexed.
Main uncertainties
Tissue expression and downstream effects vary by cell state, dose and experimental context.

Target profile

Canonical details

Canonical name
GHSR
Aliases
GHS-R1a, Ghrelin receptor
Target type
Receptor
Receptor class
Class A G protein-coupled receptor
Endogenous ligands
Ghrelin
Downstream signaling
Gq/11 → PLC → Intracellular calcium

Curated relationships

direct

Ghrelin / GHSR acts on GHSR.

mixed
direct

GHSR expressed in Pituitary.

scope not indexed
direct

Ipamorelin acts on GHSR.

scope not indexed
direct

GHRP-2 acts on GHSR.

scope not indexed
direct

GHRP-6 acts on GHSR.

scope not indexed
direct

Hexarelin acts on GHSR.

scope not indexed

Pathways, tissues and cells

Related Compounds

Published evidence

Studies

No studies in this evidence category are indexed for this node.

No dead ends

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