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AnimalRat

In vivo stimulation of connective tissue accumulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ in rat experimental wounds

F. X. Maquart, G. Bellon, B. Chaqour, J. Wegrowski, L. M. Patt, R. E. Trachy, et al.

Journal of Clinical Investigation1993DOI 10.1172/JCI116842PubMed 8227353

Study design

Methods snapshot

Population
Experimental rat wounds
Sample size
Not indexed
Intervention
GHK-Cu
Route
Not indexed
Dose reported
Not indexed
Frequency
Not indexed
Duration
Not indexed
Control / placebo
Not indexed

Outcomes

Primary

  • Connective-tissue accumulation in wounds

Results

The study reported increased connective-tissue accumulation in an experimental rat-wound model.

Interpretation

Preclinical wound-matrix evidence.

Adverse events

Not indexed in the current record.

Limitations

  • Animal wound model
  • Not evidence of human cosmetic benefit

Connected records

Original source

Sempre consulte o artigo original para métodos completos, análises e contexto editorial.

Open PubMed record ↗