Tesamorelin
Stabilized GHRH analogue
Human RCT
1 study
Open record →Research Area
Metabolic Research
Sinalização de energia, glicose, apetite, tecido adiposo e composição corporal.
At a glance
Research Summary
- What is it?
- Sinalização de energia, glicose, apetite, tecido adiposo e composição corporal.
- Why does it matter?
- `This hub organizes ${processes.length} biological processes without treating a research category as a causal mechanism.`
- Key mechanisms
- GLP-1 Signaling · AMPK · Glucagon Signaling · GHRH Signaling · GH / IGF-1 Axis
- Key targets
- Not indexed yet
- Related compounds
- Tesamorelin · Retatrutide · Tirzepatide · Semaglutide · AOD-9604
- Human evidence
- 2 directly or transitively connected human/curated study records are currently indexed.
- Main uncertainties
- Coverage is selective. A missing connection means it has not been curated here, not that no relationship exists.
Choose a level
What do you want to explore?
01
Appetite Regulation
biological process
Neural and peripheral signals that influence hunger, satiation and food intake.
6 pathway4 target6 compound2 study→
02Glucose Regulation
biological process
Hormonal control of glucose-dependent insulin secretion and systemic glucose handling.
6 pathway4 target6 compound2 study→
03Energy Expenditure
biological process
Cellular and organism-level processes that determine energy use.
5 pathway4 target8 compound2 study→
04Adipose Biology
biological process
Storage, mobilization and endocrine functions of adipose tissue.
5 pathway4 target5 compound2 study→
Key pathways
PA
GLP-1 Signaling
pathway
Sinalização de GLP-1R relacionada a secreção de insulina, esvaziamento gástrico e circuitos de saciedade.
6 pathway4 target19 compound7 study→
PAAMPK
pathway
Sensor celular de energia que coordena respostas ao estado energético.
5 pathway4 target11 compound2 study→
PAGlucagon Signaling
pathway
Sinalização de GCGR com efeitos metabólicos predominantes no fígado e dependentes do estado nutricional.
2 pathway3 target8 compound→
PAGHRH Signaling
pathway
Ativação de GHRHR em somatotrofos com sinalização Gs, adenilil ciclase, cAMP e PKA.
6 pathway3 target21 compound6 study→
PAGH / IGF-1 Axis
pathway
Eixo endócrino que conecta sinalização hipotalâmica e pituitária à produção e ação de IGF-1.
14 pathway6 target27 compound7 study→
PAcAMP Signaling
pathway
Rede de segundo mensageiro gerada por adenilil ciclase e interpretada por efetores como PKA e EPAC.
6 pathway5 target20 compound7 study→
Connected records
Related Compounds
Retatrutide
GIPR / GLP-1R / GCGR agonist
Data not indexed yet
0 studies
Open record →Tirzepatide
GIPR / GLP-1R agonist
Data not indexed yet
0 studies
Open record →Semaglutide
GLP-1 receptor agonist
Human RCT
1 study
Open record →AOD-9604
Modified hGH fragment
Mecanismo estruturado ainda não indexado.
Data not indexed yet
0 studies
Open record →Published evidence